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literature

American Urological Association and Journal of Urology

Does Low Intensity Extracorporeal Shock Wave Therapy Have a Physiological Effect on Erectile Function? Short-term Results of a Randomized, Double-Blind, Sham Controlled Study
https://www.auajournals.org/article/S0022-5347(11)06066-6/abstract

Conclusions:

This is the first randomized, double-blind, sham controlled study to our knowledge that shows that low intensity extracorporeal shock wave therapy has a positive short-term clinical and physiological effect on the erectile function of men who respond to oral phosphodiesterase type 5 inhibitor therapy. The feasibility and tolerability of this treatment, coupled with its potential rehabilitative characteristics, make it an attractive new therapeutic option for men with erectile dysfunction.

Canadian Journal of Urology

Low Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction: A Study in an Indian Population
https://pubmed.ncbi.nlm.nih.gov/25694008/

Conclusions

In this double-blind, placebo-controlled study, LI-ESWT demonstrated a positive long term clinical effect with improvement in erectile function of Indian men with vasculogenic ED who were prior responders to PDE5i therapy. The efficacy and tolerability of this treatment, coupled with its long term benefits and rehabilitative characteristics, make it an attractive new therapeutic option for men with vasculogenic erectile dysfunction.

Journal of Sexual Medicine

Low-intensity Extracorporeal Shock Wave Therapy–A Novel Effective Treatment for Erectile Dysfunction in Severe ED Patients Who Respond Poorly to PDE5 Inhibitor Therapy
https://www.jsm.jsexmed.org/article/S1743-6095(15)33720-6/abstract

Conclusions

Penile LI‐ESWT is a new modality that has the potential to treat a subgroup of severe ED patients. These preliminary data need to be reconfirmed by multicenter sham control studies in a larger group of ED patients. Gruenwald I, Appel B, and Vardi Y. Low‐intensity extracorporeal shock wave therapy—A novel effective treatment for erectile dysfunction in severe ED patients who respond poorly to PDE5 inhibitor therapy.

American Urological Association and Journal of Urology

Penile Low Intensity Shock Wave Treatment is Able to Shift PDE5i Nonresponders to Responders: A Double-Blind, Sham Controlled Study
 

Conclusions:

Low intensity shock wave treatment is effective even in patients with severe erectile dysfunction who are PDE5i nonresponders. After treatment about half of them were able to achieve erection hard enough for penetration with PDE5i. Longer followup is needed to establish the place of low intensity shock wave treatment in these challenging cases.

European Association of Urology

https://pubmed.ncbi.nlm.nih.gov/20451317/
Can Low-Intensity Extracorporeal Shockwave Therapy Improve Erectile Function? A 6-month Follow-Up Pilot Study in Patients With Organic Erectile Dysfunction

Conclusions:

This is the first study that assessed the efficacy of LI-ESWT for ED. This approach was tolerable and effective, suggesting a physiologic impact on cavernosal hemodynamics. Its main advantages are the potential to improve erectile function and to contribute to penile rehabilitation without pharmacotherapy. The short-term results are promising, yet demand further evaluation with larger sham-control cohorts and longer follow-up.

International Journal of Urology

https://pubmed.ncbi.nlm.nih.gov/24942563/

Conclusion:

The present trial shows the tolerability and clinical efficacy of low-intensity extracorporeal shockwave therapy in a subgroup of patients with erectile dysfunction.
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